Creatine and whey protein can be taken at the same time and there is no evidence to suggest that they interfere with each other. However, the timing of taking them can affect their effectiveness. Creatine supplementation is often recommended to be taken prior to a workout, as it has been shown to increase energy levels, endurance, and muscle strength during exercise. On the other hand, whey protein is often consumed after a workout to support muscle recovery and growth. It is quickly absorbed and helps to replenish glycogen stores, reducing muscle damage and promoting muscle synthesis.
For best results, it is recommended to take creatine 30-45 minutes prior to your workout and consume whey protein within 30 minutes after your workout. This timing allows for creatine to reach maximum plasma levels for improved performance during your workout, and for whey protein to support optimal muscle recovery and growth after the workout. However, everyone's needs and goals may be different, so you may need to adjust your timing to meet your individual needs.